12mg
NMN
Nicotinamide mononucleotideThe direct building block of NAD+. Your cells convert NMN to NAD+ in a single step, which is why it's become the most researched NAD+ precursor of the last decade.
Liposomal NAD+ nasal spray
Cellular energy support, one spray at a time
PureVita Wellness Liposomal NAD+ Complete pairs NAD+ with its two best-studied precursors, NMN and NR, in a fine liposomal mist that absorbs through the nasal lining. No pills to swallow, no needles, no clinic visit.
- Triple NAD+ complex: 12 mg NMN, 10 mg NAD+ and 3 mg NR per serving
- Liposome-encapsulated to protect the actives and support absorption
- Supports cellular energy, mental clarity and healthy aging*
- Two quick sprays that fit any morning routine
Subscribe and save: $59
60-day money-back guarantee
Free shipping on 3+ bottles
Needle-free, pill-free
3-in-1NAD+, NMN and NR
LiposomalNasal delivery
25 mgTotal NAD+ actives per serving
3forms of NAD+ support
25 mgactive complex per serving
2 spraysone per nostril, once a day
0pills, powders or needles
Why NAD+ matters
Every cell runs on NAD+. Most of us make less with time.
NAD+ (nicotinamide adenine dinucleotide) is a coenzyme found in every living cell. Your mitochondria use it to turn food into usable energy, and the enzymes that maintain your DNA and regulate cellular stress responses depend on it too.3
The catch is that NAD+ levels don't hold steady for life. Researchers measuring NAD+ in human skin and brain tissue have found lower levels in older adults than in younger ones.1,2 That gradual decline is one reason healthy-aging research has turned so much attention to NAD+ and its precursors.9
Energy
A core coenzyme in the mitochondrial pathways that produce ATP.
Maintenance
Fuel for the enzymes involved in normal DNA upkeep.
Rhythm
Linked to the cellular signals that keep daily rhythms in sync.
Designed for people who want NAD+ support without another handful of capsules.
The complete NAD+ pathway
Three routes to NAD+, in one mist
Your body builds NAD+ through a recycling system called the salvage pathway. PureVita supplies the finished coenzyme plus two precursors your cells convert along that route.
Precursor, 2 steps awayNR
Nicotinamide riboside is converted to NMN inside your cells, then to NAD+.7
Precursor, 1 step awayNMN
Nicotinamide mononucleotide is the immediate building block of NAD+.9
The coenzyme itselfNAD+
Delivered ready-made, alongside the precursors that help replenish it.
Why combine all three? Different tissues rely on different entry points into the NAD+ pathway, so a complete formula doesn't bet on a single route.
Why liposomal nasal delivery
A shorter path from bottle to bloodstream
What you swallow has to survive stomach acid, digestive enzymes and a first pass through the liver before it reaches circulation. The nasal route skips that journey.
Protected in liposomes
NAD+, NMN and NR are enclosed in liposomes: microscopic spheres made from phospholipids, the same material as your cell membranes. They shield the actives in the bottle and help them interact with the nasal lining.
Absorbed through the nasal lining
The inside of your nose has a thin, blood-vessel-rich surface. Compounds absorbed there enter circulation without passing through the digestive tract or the liver first.8
Small doses, used daily
Because nasal delivery avoids digestive breakdown, it works with far smaller amounts than oral capsules. Daily use keeps the support consistent rather than occasional.
| How you take NAD+ support | Capsules and powders | IV drips | PureVita nasal spray |
|---|---|---|---|
| Digestion and liver first pass | Yes, before absorption | Bypassed | Bypassed |
| Needles or clinic visit | No | Yes, 1 to 4 hours per session | No |
| Time per day | Seconds | Hours, per session | About 10 seconds |
| Forms of NAD+ support | Usually one precursor | NAD+ only | NAD+, NMN and NR |
| Human research | Most studied (oral NMN and NR) | Limited | Early, growing |
We list the research honestly: most human NAD+ precursor studies used oral NMN or NR, and research on intranasal NAD+ in people is still early.
Inside every serving
The NAD+ Complete formula
Three actives, fully disclosed, with no proprietary blends. Here's what each one does and what the research says.
10mg
NAD+
Nicotinamide adenine dinucleotideThe finished coenzyme, delivered as is. Including NAD+ itself means your body isn't relying only on conversion from precursors.
3mg
NR
Nicotinamide ribosideA form of vitamin B3 that your cells convert to NMN and then to NAD+. It adds a second, independent route into the NAD+ pathway.
In the research: in healthy adults aged 55 to 79, oral NR (1,000 mg a day for six weeks) raised NAD+ in blood cells and was well tolerated.6
Why are these amounts smaller than capsule doses? Oral studies use hundreds of milligrams because much of the dose is broken down during digestion. Nasal delivery avoids that step, so doses aren't directly comparable.
What it supports
Support that starts at the cellular level*
Cellular energy
Supplies the coenzyme your mitochondria use to convert food into energy.*
Mental clarity and focus
Your brain is one of the most energy-hungry organs. NAD+ helps power it.*
Healthy aging
Helps maintain NAD+ levels that naturally decline with age.*
Cellular maintenance
Supports the enzymes behind your body's normal DNA upkeep.*
Healthy metabolism
NAD+ is a central player in how your cells process nutrients.*
An easy daily habit
Two sprays in about ten seconds. Consistency is what counts with NAD+.
What to expect
Your first 90 days
NAD+ support is cumulative, not instant. Here's a realistic picture of how the first three months tend to go.
Week 1
Build the habit
Use it at the same time each morning. Some people notice they feel more alert early on, while many notice nothing yet, which is completely normal at this stage.
Weeks 2 to 4
Consistency takes over
With daily use, some people report steadier energy through the afternoon and clearer focus. Keep a short note of your energy, focus and sleep so you can compare later.
Months 2 to 3
Take stock
This is the fairest point to judge how it's working for you. Compare your notes with week one. If it isn't right for you, our 60-day guarantee covers you.
Beyond 90 days
Make it part of your routine
Healthy aging is a long game. Most people who stay with NAD+ support treat it like any other daily wellness habit.
Individual experiences vary. These are general expectations, not promised results.
How to use
Four steps, ten seconds
1
Shake gently
Liposomes can settle. A gentle shake mixes them evenly.
2
Prime the pump
On first use, spray into the air a few times until a fine mist appears.
3
Spray and breathe
Tilt your head slightly forward. One spray in each nostril, breathing in gently.
4
Store it cold
Keep refrigerated after opening, unless your label says otherwise, to protect the actives.
A pharmacist's perspective"NAD+ is one of the most interesting areas in healthy-aging research, and it's also one of the most overhyped. What I like about this formula is that it's transparent: three actives, exact amounts, no proprietary blend, and no claim that a spray turns back the clock. The oral NMN and NR research is encouraging, while human research on nasal NAD+ is still early. If you take prescription medicines, are pregnant or breastfeeding, or have a chronic condition, check with your doctor or pharmacist first."
Manzoor KhanPharmacist, 9+ years writing about supplements
Use it safely
Good to know before you start
Talk to your doctor first if you
- Are pregnant, trying to conceive or breastfeeding
- Take prescription medication or have a medical condition
- Have a chronic nasal condition, recent nasal surgery or frequent nosebleeds
- Are under 18 (not intended for children)
What you might notice
- Brief tingling or stinging in the nose after spraying
- Occasional sneezing or a mild runny nose
- Rarely, a mild headache
- If any effect persists, stop using it and speak to a healthcare professional
Choose your supply
Start your NAD+ routine
Most people choose a three-month supply, the fairest window to judge how NAD+ support works for them.
- Free shipping on 3 and 6 bottle packs
- Subscribe and save 15% on any pack, cancel anytime
- 60-day money-back guarantee, even on empty bottles
Questions
NAD+ nasal spray FAQ
NAD+ (nicotinamide adenine dinucleotide) is a coenzyme found in every cell. It helps your mitochondria turn food into energy and fuels enzymes involved in normal cellular maintenance. Studies measuring NAD+ in human tissue have found lower levels in older adults, which is why NAD+ support has become a focus of healthy-aging research.
Capsules pass through stomach acid, digestive enzymes and the liver before reaching circulation, and much of the dose is broken down along the way. The nasal lining is thin and rich in blood vessels, so a nasal spray skips that journey and works with much smaller amounts. It's also needle-free and takes about ten seconds.
Liposomes are microscopic spheres made from phospholipids, the same material as your cell membranes. Enclosing NAD+, NMN and NR inside them helps protect the actives in the bottle and supports their interaction with the nasal lining.
Most capsules contain a single precursor. PureVita combines NAD+ itself with both NMN and NR, three entry points into the same pathway, in a nasal format. Oral NMN and NR have the most human research so far; research on nasal NAD+ in people is still early, and we say so openly.
NAD+ support is cumulative. Some people notice feeling more alert in the first week or two, while others notice gradual changes over several weeks. We suggest judging it after two to three months of daily use, which is why the guarantee lasts 60 days.
Most people feel only a light mist. Some notice brief tingling, stinging or a sneeze right after spraying, which usually fades within seconds. Tilting your head slightly forward and breathing in gently helps.
Many people use it alongside a multivitamin or other wellness supplements. If you already take an NAD+ precursor such as NMN capsules, or you take any prescription medication, check with your doctor or pharmacist first.
Keep it in the refrigerator after opening, unless your label says otherwise, and away from direct light and heat. Don't freeze it. Keep it out of reach of children.
No. Wellness products like this are not FDA approved, and the statements on this page have not been evaluated by the FDA. The product is not intended to diagnose, treat, cure or prevent any disease.
You're covered by a 60-day money-back guarantee. If you're not happy, contact support for a full refund, even if the bottle is empty.
References
The research behind the copy
Every claim above links to one of these sources.
- Massudi H, et al. Age-associated changes in oxidative stress and NAD+ metabolism in human tissue. PLoS One. 2012;7(7):e42357.
- Zhu XH, et al. In vivo NAD assay reveals the intracellular NAD contents and redox state in healthy human brain and their age dependences. Proc Natl Acad Sci USA. 2015;112(9):2876-2881.
- Verdin E. NAD+ in aging, metabolism, and neurodegeneration. Science. 2015;350(6265):1208-1213.
- Yoshino M, et al. Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women. Science. 2021;372(6547):1224-1229.
- Igarashi M, et al. Chronic nicotinamide mononucleotide supplementation elevates blood nicotinamide adenine dinucleotide levels and alters muscle function in healthy older men. npj Aging. 2022;8:5.
- Martens CR, et al. Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adults. Nat Commun. 2018;9:1286.
- Trammell SAJ, et al. Nicotinamide riboside is uniquely and orally bioavailable in mice and humans. Nat Commun. 2016;7:12948.
- Dhuria SV, Hanson LR, Frey WH 2nd. Intranasal delivery to the central nervous system: mechanisms and experimental considerations. J Pharm Sci. 2010;99(4):1654-1673.
- Rajman L, Chwalek K, Sinclair DA. Therapeutic potential of NAD-boosting molecules: the in vivo evidence. Cell Metab. 2018;27(3):529-547.
Give your cells the complete picture
NAD+, NMN and NR in one liposomal mist, backed by a 60-day guarantee.
Choose your supplyNAD+ Complete Nasal SprayFrom $49 per bottleChoose supply
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